Pular para o conteúdo
Merck

DAXX

death-domain associated protein

Sinônimos:
BING2, DAP6, EAP1
Espécies:
ID UniProtKB:
ID do gene:
  • Human(1616) Summary: This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
  • Mouse(13163) Fas death domain-associated protein
  • Rat(140926) death-domain associated protein
  • naked mole-rat(101717412) death-domain associated protein
  • domestic guinea pig(100730008) death-domain associated protein
  • sheep(100505403) death-domain associated protein
  • Zebrafish(561006) death-associated protein 6
  • dog(474873) death-domain associated protein
  • cow(504336) death-domain associated protein
  • domestic cat(101089265) death-domain associated protein

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-DAXX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-DAXX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-DAXX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
Monoclonal Anti-DAXX antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL3580, purified immunoglobulin, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
Anti-Daxx antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reatividade de espécies
human, mouse
Aplicação
ELISA
immunocytochemistry

western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human DAXX,
Espécies
MISSION® esiRNA, targeting mouse Daxx,
Espécies
mouse