CTSB
cathepsin B
Sinônimos:
APPS, CPSB
Espécies:
Human CTSB (1508), Mouse Ctsb (13030), Rat Ctsb (64529), chicken CTSB (396329), dog CTSB (486077), domestic cat CTSB (101084873), cow CTSB (281105), Horse CTSB (100060963), sheep CTSB (780470), naked mole-rat Ctsb (101709008)
ID UniProtKB:
ID do gene:
- Human(1508) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(13030) cathepsin B
- Rat(64529) cathepsin B
- chicken(396329) cathepsin B
- dog(486077) cathepsin B
- domestic cat(101084873) cathepsin B
- cow(281105) cathepsin B
- Horse(100060963) cathepsin B
- sheep(780470) cathepsin B
- naked mole-rat(101709008) cathepsin B
- domestic guinea pig(100714169) cathepsin B
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Antibodies
Product Number
Descrição
Reatividade de espécies
Aplicação
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Cathepsin B (Ab-1) Mouse mAb (CA10), lyophilized, clone CA10, Calbiochem®,
Reatividade de espécies
bovine, human, porcine
Aplicação
Anti-Cathepsin B Antibody, clone 6I5D7, Rabbit Monoclonal, ,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
western blot
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Cathepsin B antibody, Mouse monoclonal, clone CB59-4B11, purified from hybridoma cell culture,
Reatividade de espécies
human, rat
Aplicação
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Descrição
Espécies
Cathepsin B from human liver, buffered aqueous solution, ≥1,500 units/mg protein (E1%/280),
Espécies
human
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Espécies
human
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Espécies
human
esiRNA
Small Molecule - Substrate
Product Number
Descrição
Espécies