sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

Natural product reports (2014-02-28)

Egor Geist, Andreas Kirschning, Thomas Schmidt

ABSTRACT

This Highlight covers the current status of relatively unexplored sp(3)-sp(3) cross-coupling reactions with particular focus on natural product and related syntheses.

MATERIALS

Product Number

Brand

Product Description

203904

Sigma-Aldrich

Nickel, powder, <150 μm, 99.99% trace metals basis

510033

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2400, slurry, in H₂O, active catalyst

268259

Sigma-Aldrich

Nickel, foil, thickness 0.125 mm, ≥99.9%

267058

Sigma-Aldrich

Nickel, wire, diam. 0.5 mm, ≥99.99% trace metals basis

268283

Sigma-Aldrich

Nickel, powder, <1 μm, 99.8% trace metals basis

267007

Sigma-Aldrich

Nickel, foil, thickness 0.25 mm, 99.995% trace metals basis

221678

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2800, slurry, in H₂O, active catalyst

GF49702406

Nickel, foil, light tested, 50x50mm, thickness 0.0075mm, 99.95%

GF00552967

Nickel, foil, 0.5m coil, thickness 0.01mm, 99.95%

GF34426470

Nickel, tube, 500mm, outside diameter 5.9mm, inside diameter 5.65mm, wall thickness 0.125mm, hard, 99.5%

GF84616207

Nickel, foil, 10mm disks, thickness 0.008mm, 99.95%

GF01316595

Nickel, wire reel, 1m, diameter 0.75mm, as drawn, 99.99+%

GF27731853

Nickel, wire reel, 10m, diameter 0.05mm, as drawn, 99%

GF64268118

Nickel, foil, 4mm disks, thickness 0.05mm, 99.9%

GF04087076

Nickel, wire reel, 10m, diameter 0.25mm, as drawn, 99%

GF86231729

Nickel, foil, 4mm disks, thickness 0.05mm, as rolled, 99.99+%

GF60595061

Nickel, wire reel, 100m, diameter 0.25mm, as drawn, 99%

GF27664836

Nickel, foil, 4mm disks, thickness 0.008mm, 99.95%

GF54355147

Nickel, wire reel, 0.2m, diameter 0.4mm, as drawn, 99.99+%

GF70648915

Nickel, foil, 2m coil, thickness 0.1mm, annealed, 99%

GF67542194

Nickel, foil, 10mm disks, thickness 0.0025mm, 99.95%

GF17802064

Nickel, wire reel, 10m, diameter 0.5mm, hard, 99.98%

GF48314763

Nickel, foil, 4mm disks, thickness 0.015mm, 99.9%

GF58972753

Nickel, foil, 0.5m coil, thickness 0.015mm, 99.9%

GF66892922

Nickel, wire reel, 100m, diameter 0.5mm, hard, 99.98%

GF68422574

Nickel, foil, 300x300mm, thickness 2.0mm, annealed, 99%

GF79742953

Nickel, wire reel, 1m, diameter 0.05mm, as drawn, 99.99+%

GF65888274

Nickel, foil, 0.5m coil, thickness 0.30mm, as rolled, 99.98%

GF97678995

Nickel, wire reel, 10m, diameter 0.25mm, as drawn, 99.99+%

GF19453091

Nickel, foil, 0.5m coil, thickness 0.02mm, 99.9%