SML3328

Methyl protodioscin

≥98% (HPLC)

• Synonym(s): (3β,​22α,​25R)​-​26-​(β-​D-​Glucopyranosyloxy)​-​22-​methoxyfurost-​5-​en-​3-​yl O-​6-​deoxy-​α-​L-​mannopyranosyl-​(1→2)​-​O-​[6-​deoxy-​α-​L-​mannopyranosyl-​(1→4)​]​-β-​D-​glucopyranoside, 22-O-Methylprotodioscin, Methylprotodioscin, NSC 698790
• Empirical Formula (Hill Notation): C₅₂H₈₆O₂₂
• CAS Number: 54522-52-0
• Molecular Weight: 1063.23
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C
• InChI: 1S/C52H86O22/c1-21(20-66-46-40(61)39(60)36(57)31(18-53)70-46)10-15-52(65-7)22(2)33-30(74-52)17-29-27-9-8-25-16-26(11-13-50(25,5)28(27)12-14-51(29,33)6)69-49-45(73-48-42(63)38(59)35(56)24(4)68-48)43(64)44(32(19-54)71-49)72-47-41(62)37(58)34(55)23(3)67-47/h8,21-24,26-49,53-64H,9-20H2,1-7H3/t21-,22+,23+,24+,26+,27-,28+,29+,30+,31-,32-,33+,34+,35+,36-,37-,38-,39+,40-,41-,42-,43+,44-,45-,46-,47+,48+,49-,50+,51+,52-/m1/s1
• InChI key: HSSJYSJXBOCKQM-GVTGEURHSA-N

Description

Biochem/physiol Actions

Methyl protodioscin is a saponin isolated from medical plant Dioscoreaceae that exhibit anticancer properties. It appears that Methyl protodioscin inhibits proliferation and promoted apoptosis of pancreatic cancer through suppression of glycolysis. Methyl protodioscin protects rat brain from I/R injury through down-regulation Mul1 (Mitochondrial E3 ubiquitin ligase 1) and elevation of SOD2 (superoxide dismutase 2) protein levels.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable