SML0512

BLT-4

≥98% (HPLC)

• Synonym(s): INF 271, MIT 9952-29, N-(2-Methoxyphenyl)-N′-2-naphthalenyl-urea
• Empirical Formula (Hill Notation): C₁₈H₁₆N₂O₂
• CAS Number: 251917-79-0
• Molecular Weight: 292.33
• MDL number: MFCD00406317
• UNSPSC Code: 51111800
• PubChem Substance ID: 329825521
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 15 mg/mL (clear solution)
• storage temp.: room temp
• SMILES string: COc1ccccc1NC(=O)Nc2ccc3ccccc3c2
• InChI: 1S/C18H16N2O2/c1-22-17-9-5-4-8-16(17)20-18(21)19-15-11-10-13-6-2-3-7-14(13)12-15/h2-12H,1H3,(H2,19,20,21)
• InChI key: ISADADAHPHHLEM-UHFFFAOYSA-N

Description

Biochem/physiol Actions

BLT-4 is a SR-BI (Scavenger receptor, class B, type I) inhibitor.

BLT-4 is a blocker of lipid transport-4 (BLT-4). BLT-4 is a specific, reversible inhibitor of scavenger receptor, class B, type I (SR-BI) mediated lipid transfer. The molecule blocks the cellular uptake and transfer of cholesterol ester from HDL.

Safety Information

• Pictograms: GHS09
• Signal Word: Warning
• Hazard Statements: H410
• Precautionary Statements: P273 - P391 - P501
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable