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Key Documents

SAB5702014

Sigma-Aldrich

Anti-Lamin B1 Antibody, clone 5H8V8, Rabbit Monoclonal

Synonym(s):

ADLD, LMN, LMN2, LMNB

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

100

material

colorless

clone

5H8V8, monoclonal

form

liquid

species reactivity

rat, rat, human

concentration

0.3 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

DGKFIRLKNTSEQDQPMGGWEMIRKIGDTSVSYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVAQRSTVFKTTI

UniProt accession no.

P20700

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... LMNB1(4001)

General description

This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 450-550 of human Lamin B1 (P20700).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Certificates of Analysis (COA)

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