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SAB4200622

Sigma-Aldrich

Anti-DISC-1 (Internal) antibody produced in rabbit

~1 mg/mL, affinity isolated antibody

Synonym(s):

C1orf136, DISC1, Disrupted in schizophrenia 1, LOC100039084, LOC640053, RP23−368K3.1, RP4−730B13.1, SCZD9

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

antibody form

affinity isolated antibody

Quality Level

200

antibody product type

primary antibodies

form

buffered aqueous solution

species reactivity

human, rat

concentration

~1 mg/mL

technique(s)

immunoblotting: 1-2 μg/mL using whole extracts of rat brain P2 fraction or HEK-293T cells over-expressing human DISC1
immunoprecipitation (IP): 2.5-5.0 μg using extracts of mouse brain.

UniProt accession no.

Q9NRI5

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... DISC1(27185)
rat ... Disc1(307940)

Immunogen

synthetic peptide corresponding to an internal sequence in rat DISC1

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Pippa A Thomson et al.
Frontiers in biology, 8(1), 1-31 (2013-04-04)
Psychiatric disorders are highly heritable, and in many individuals likely arise from the combined effects of genes and the environment. A substantial body of evidence points towards DISC1 being one of the genes that influence risk of schizophrenia, bipolar disorder
Atsushi Kamiya et al.
Frontiers in psychiatry, 3, 25-25 (2012-03-31)
Genetic risk factors for major psychiatric disorders play key roles in neurodevelopment. Thus, exploring the molecular pathways of risk genes is important not only for understanding the molecular mechanisms underlying brain development, but also to decipher how genetic disturbances affect

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