SAB2702179

Anti-ERCC3 antibody produced in rabbit

• Synonym(s): GTF2H, RAD25, TFIIH, XPB
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: polyclonal
• form: liquid
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): immunocytochemistry: suitable; immunofluorescence: suitable; western blot: 1:500
• UniProt accession no.: P19447
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... ERCC3(2071)

Description

Immunogen

Peptide corresponding to the carboxy-terminus of human XPB.

Application

For WB: Use at a dilution of 1:500 and incubate at RT for 40 minutes. Blocking solution: 3% Milk/TBST at RT for one hour. Optimal dilutions/concentrations should be determined by the researcher.

Biochem/physiol Actions

The human XPB DNA helicase is a subunit of the DNA repair/basal transcription factor TFIIH, and is involved in early steps of the nucleotide excision repair (NER) pathway. Two distinct clinical phenotypes, xeroderma pigmentosum associated with Cockayne′s syndrome (XP/CS) and trichothiodystrophy (TTD), can be due to mutations in the XPB gene.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Phosphate-buffered saline, pH 7.2, containing no preservatives

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable