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SAB1306277

ANTI-OSTEOCALCIN(N-TERMINAL) antibody produced in rabbit

Name: ANTI-OSTEOCALCIN(N-TERMINAL) antibody produced in rabbit
Brand: SIGMA

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

BGLAP, Bone Gla protein, Gamma-carboxyglutamic acid-containing protein, Osteocalcin

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

biological source

rabbit

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

10963 Da

species reactivity

human

technique(s)

immunohistochemistry: 1:50-1:100
western blot: 1:1000

NCBI accession no.

NP_954642.1

UniProt accession no.

P02818

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BGLAP(632)

General description

Bone γ-carboxyglutamate protein (BGLAP) or osteocalcin (OCN) is a non-collagenous bone matrix protein expressed by osteoblasts. It possesses a Gla (γ-carboxyglutamate) domain. The gene encoding OCN is localized on human chromosome 1q22.

Application

ANTI-OSTEOCALCIN(N-TERMINAL) antibody produced in rabbit has been used in western blotting and immnuohistochemistry.

Biochem/physiol Actions

Bone γ-carboxyglutamate protein (BGLAP) regulates osteogenic differentiation of mesenchymal stromal cells. It has a role in bone turnover and mineralization. The protein also has a role in energy metabolism. BGLAP may act as a mediator between glucose metabolism and bone tissue.

Physical form

Supplied in PBS with 0.09% (W/V) sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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