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S2770

Sigma-Aldrich

Sodium hydroxide solution

1.0 N, BioReagent, suitable for cell culture

Synonym(s):

Caustic Soda, Lye, NaOH, Soda

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About This Item

Linear Formula:
NaOH
CAS Number:
1310-73-2
Molecular Weight:
40.00
MDL number:
MFCD00003548
UNSPSC Code:
12352316
PubChem Substance ID:
24899535
NACRES:
NA.71

vapor pressure

3 mmHg ( 37 °C)

Quality Level

200

sterility

sterile-filtered

product line

BioReagent

form

solution

concentration

1.0 N

technique(s)

cell culture | mammalian: suitable

SMILES string

[OH-].[Na+]

InChI

1S/Na.H2O/h;1H2/q+1;/p-1

InChI key

HEMHJVSKTPXQMS-UHFFFAOYSA-M

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General description

Sodium hydroxide is a strong alkali. Its reaction with acid yields salt and water. Sodium hydroxide solution has many industrial applications including dyes and drugs. It has the ability to disintegrate lignin and hence is used in paper manufacturing. Sodium hydroxide has high melting of about 318°C.

Application

Sodium hydroxide solution has been used:
  • to neutralize collagen type I solution phosphate-buffered saline for its use in 3D cell culture technique
  • to dissolve phosphate chains in phosphate glass for optical characterisation
  • as a component of transfer medium used for cell culture
  • as a general titration base for cell culture applications.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H290,H314

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Matrix dimensions, stiffness, and structural properties modulate spontaneous chondrogenic commitment of mouse embryonic fibroblasts
Fernandez MT
Tissue Engineering: Part A, 20(7-8), 1145-1155 (2013)
Sodium, 21-21 (2002)
Isolation and culture of human endometrial epithelial cells and stromal fibroblasts
Chen JC and Roan NR
Bio-protocol, 5(20) (2015)
Optical characterisation of hydroxide catalysed bonds applied to phosphate glass
Optifab, 10448, 1044825-1044825 (2017)
Konstantinos A Polyzos et al.
Cardiovascular research, 106(2), 295-302 (2015-03-10)
Atherosclerosis is a chronic inflammatory disease that is initiated by the retention and accumulation of low-density lipoprotein in the artery, leading to maladaptive response of cells from the immune system and vessel wall. Strong evidence implicates indoleamine 2,3-dioxygenase (IDO), the
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Protocols

Media Preparation – Plant Tissue Culture Protocol

Preparation from Packaged Powder, Preparation from Basal Salt Solutions, Banana Powder Preparation and Use, Coconut Water Preparation and Use

Cultrex® 3-D Culture Matrix™ Rat Collagen I Protocol

3-D Culture Matrix™ Collagen I may be used as a gel on which to grow cells or a media additive alone or in concert with other basement membrane components to study cellular growth and differentiation in three dimensions in vitro.

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