RAB0290
Human IL-22 ELISA Kit
for serum, plasma, cell culture supernatant and urine
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About This Item
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Quality Level
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type plasma
sample type cell culture supernatant(s)
sample type serum
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8 pg/mL
standard curve range: 6.55-1600 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... IL22(50616)
General description
Human Interleukin-22 (IL-22) enzyme-linked immunosorbent assay (ELISA) Kit is an in vitro assay for the quantitative measurement of human IL-22 in biological samples, such as serum, plasma, cell culture supernatants, urine, and/or cell and tissue lysates. IL-22 belongs to the family of IL-10 of cytokines. It is produced by the γδ T cells, CD4+ T helper cells, natural killer T cells, and innate lymphoid cells. It is involved in the activation of signal transducer and activator of transcription 3 and 1 (STAT3/1). IL-22 possesses stage-specific, pro-and anti-tumor effects.
Immunogen
Recombinant Human IL-22
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Kit Components Also Available Separately
Product No.
Description
SDS
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
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The Th17 cytokines interleukin-17A (IL-17A), IL-17F, and IL-22 are critical for the lung immune response to a variety of bacterial pathogens, including Klebsiella pneumoniae. Th2 cytokine expression in the airways is a characteristic feature of asthma and allergic airway inflammation.
Hormones (Athens, Greece), 13(3), 338-344 (2014-08-01)
Hashimoto's thyroiditis (HT) is considered to be a Th1-related autoimmune disease (AID). Recent studies revealed that Th17 lymphocytes (producing mostly IL-17, IL-21 and IL-22) play a major role in numerous AIDs commonly thought to be Th1 diseases. More recently, another
Human B cells induce dendritic cell maturation and favour Th2 polarization by inducing OX-40 ligand.
Nature communications, 5, 4092-4092 (2014-06-10)
Dendritic cells (DCs) play a critical role in immune homeostasis by regulating the functions of various immune cells, including T and B cells. Notably, DCs also undergo education on reciprocal signalling by these immune cells and environmental factors. Various reports
Journal of immunology (Baltimore, Md. : 1950), 192(12), 5635-5642 (2014-05-09)
Naive CD4 lymphocytes undergo a polarization process in the periphery to become induced Th17 (iTh17) cells. Using retinoic acid-related orphan receptor γt (RORγt)-gfp mice, we found that RORγt and the transcription factor promyelocytic leukemia zinc finger (PLZF) are valuable new
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