P7857
Anti-P2X1 Purinergic Receptor antibody produced in rabbit
affinity isolated antibody, lyophilized powder
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About This Item
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
rat, human
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot (chemiluminescent): 1:200
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... P2RX1(5023)
mouse ... P2rx1(18436)
rat ... P2rx1(25505)
Related Categories
Immunogen
synthetic peptide corresponding to amino acids 382-399 of rat P2X1 (with additional N-terminal cysteine and serine). The epitope is highly conserved in mouse and human.
Physical form
Lyophilized at ~0.6 mg/ml from a solution of phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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The American journal of physiology, 274(4 Pt 2), F799-F804 (1998-05-12)
P2 receptors have been identified in rat kidney by autoradiography, using the radioligand [3H] alpha, beta-methylene ATP, and by immunohistochemistry, using a polyclonal antibody to the P2X1 purinoceptor. They have been localized to the vascular smooth muscle of intrarenal arteries
American journal of physiology. Renal physiology, 310(9), F909-F922 (2016-01-30)
Type II diabetes is the most prevalent form of diabetes. One of the primary complications of diabetes that significantly affects quality of life is bladder dysfunction. Many studies on diabetic bladder dysfunction have been performed in models of type I
Molecular and cellular biology, 11(8), 4177-4188 (1991-08-01)
Programmed cell death is an essential cellular process that occurs in epithelial turnover, neural development, and regulation of cell populations of the immune system. Thymocytes undergo programmed cell death in response to several inductive stimuli, including exposure to glucocorticoids or
Nature, 371(6497), 516-519 (1994-10-06)
Extracellular ATP exerts its effects through P2 purinoceptors: these are ligand-gated ion channels (P2x) or G-protein-coupled receptors (P2Y, P2U). ATP at P2x receptors mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic
Proceedings of the National Academy of Sciences of the United States of America, 93(15), 8063-8067 (1996-07-23)
Several P2X receptor subunits were recently cloned; of these, one was cloned from the rat vas deferens (P2X1) and another from pheochromocytoma (PC12) cells differentiated with nerve growth factor (P2X2). Peptides corresponding to the C-terminal portions of the predicted receptor
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