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M5757

Sigma-Aldrich

Maleic acid sodium salt

~99%

Synonym(s):

cis-Butenedioic acid, Toxilic acid

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About This Item

Linear Formula:
C4H3O4Na
CAS Number:
3105-55-3
Molecular Weight:
138.05
EC Number:
221-461-6
MDL number:
MFCD00070246
UNSPSC Code:
12352106
PubChem Substance ID:
24897040

Assay

~99%

Quality Level

200

SMILES string

OC(/C=C\C([O-])=O)=O.[Na+]

InChI

1S/C4H4O4.Na/c5-3(6)1-2-4(7)8;/h1-2H,(H,5,6)(H,7,8);/q;+1/p-1/b2-1-;

InChI key

VRVKOZSIJXBAJG-ODZAUARKSA-M

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Biochem/physiol Actions

Maleic acid is a component of cosmetics, fragrances and has industrial applications. It is also a potent nephrotoxin and is implicated to induce glycosuria, aminoaciduria and Fanconi syndrome.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315 - H319 - H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Maleic acid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1272

Maleic acid

Sodium malonate dibasic ≥97.0% (NT)

Sigma-Aldrich

63409

Sodium malonate dibasic

Mei-Ling Hou et al.
Molecules (Basel, Switzerland), 21(3), 367-367 (2016-03-22)
Maleic acid has been shown to be used as a food adulterant in the production of modified starch by the Taiwan Food and Drug Administration. Due to the potential toxicity of maleic acid to the kidneys, this study aimed to
Nidambur Vasudev Ballal et al.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 112(5), 696-700 (2011-08-30)
The aim of this study was to evaluate the antimicrobial efficacy of 7% maleic acid (MA) and 17% ethylenediaminetetraacetic acid (EDTA) in elimination of Enterococcus faecalis, Candida albicans, and Staphylococcus aureus at different time intervals. Transfer culture of microbial strains
Ke Chen et al.
Dalton transactions (Cambridge, England : 2003), 41(17), 5391-5400 (2012-04-05)
A series of enantiomerically pure 1,2-diester substituted P,N-ligands incorporating two chiral carbons in the backbone were generated in high yields and high stereoselectivity from acetylenedicarboxylate via initial hydrophosphination using diphenylphosphine followed by hydroamination with various primary and secondary amines. The
Jing-hang Xu et al.
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 20(7), 512-516 (2012-10-10)
To evaluate the efficacy and safety of entecavir (ETV) maleate versus ETV in Chinese patients with hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB). This was a randomized, double-blind, double-dummy, controlled, multicenter study. Patients were randomly assigned to receive
Stéphane Pietravalle et al.
Environmental pollution (Barking, Essex : 1987), 176, 42-47 (2013-02-16)
Multiple substrate induced respiration (MSIR) assays which assess the response of soils to carbon source amendment are effective approaches to determine catabolic diversity of soils. Many assays are based on a single short term (<6 h) time point measurement and
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