All Photos(4)

Documents

K3250

Kynuramine dihydrobromide

Name: Kynuramine dihydrobromide
Brand: SIGMA

monoamine oxidase substrate, fluorogenic, ≥97% (TLC), crystalline

Synonym(s):

3-(2-Aminophenyl)-3-oxopropanamine

Sign Into View Organizational & Contract Pricing

All Photos(4)

About This Item

Empirical Formula (Hill Notation):

C₉H₁₂N₂O · 2HBr

CAS Number:

304-47-2

Molecular Weight:

326.03

MDL number:

MFCD00050683

UNSPSC Code:

12352204

PubChem Substance ID:

24896227

NACRES:

NA.32

product name

Kynuramine dihydrobromide, crystalline

Assay

≥97% (TLC)

form

crystalline

solubility

water: 50 mg/mL, clear to slightly hazy

storage temp.

−20°C

SMILES string

Br.NCCC(=O)c1ccccc1N

InChI

1S/C9H12N2O.BrH/c10-6-5-9(12)7-3-1-2-4-8(7)11;/h1-4H,5-6,10-11H2;1H

InChI key

YUPVVZSYBUIDQR-UHFFFAOYSA-N

Application

Kynuramine dihydrobromide has been used as a substrate for monoamine oxidase.

Biochem/physiol Actions

Kynuramine dihydrobromide is a substrate for the enzyme monoamine oxidase. The end product is the formation of fluorescence detectable 4-hydroxyquinoline (4-HOQ) measured in a fluorescence spectrophotometer at 380 nm.

Substrates

Substrate for monoamine oxidase

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Evidence for the involvement of the noradrenergic system, dopaminergic and imidazoline receptors in the antidepressant-like effect of tramadol in mice

Jesse CR, et al.

Pharmacology, Biochemistry, and Behavior, 95(3), 344-350 (2010)

An investigation of the monoamine oxidase inhibition properties of pyrrolo[3,4-f]indole-5,7-dione and indole-5,6-dicarbonitrile derivatives.

Zhanna V Chirkova et al.

Drug development research, 79(2), 81-93 (2018-03-24)

Hit, Lead & Candidate Discovery In recent studies, we have shown that pyrrolo[3,4-f]indole-5,7-dione and indole-5,6-dicarbonitrile derivatives act as good potency in vitro inhibitors of the monoamine oxidase (MAO) enzymes. To expand on these series and to further derive structure-activity relationships

Chronic dietary mercury exposure causes oxidative stress, brain lesions, and altered behaviour in Atlantic salmon (Salmo salar) parr

Berntssen MHG, et al.

Aquatic Toxicology (Amsterdam, Netherlands), 65(1), 55-72 (2003)

2-Heteroarylidene-1-indanone derivatives as inhibitors of monoamine oxidase.

Magdalena S Nel et al.

Bioorganic chemistry, 69, 20-28 (2016-09-24)

In the present study a series of fifteen 2-heteroarylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B. These compounds are structurally related to series of heterocyclic chalcone derivatives which have previously been

Synergistic antidepressant-like effect of ferulic acid in combination with piperine: involvement of monoaminergic system

Li G, et al.

Metabolic Brain Disease, 30(6), 1505-1514 (2015)

View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service