Skip to Content
Merck
All Photos(1)

Key Documents

I0658

Sigma-Aldrich

IC 261

≥98% (HPLC)

Synonym(s):

1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one, SU5607

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C18H17NO4
CAS Number:
Molecular Weight:
311.33
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

storage condition

protect from light

color

yellow

solubility

DMSO: >10 mg/mL

SMILES string

COc1cc(OC)c(\C=C2/C(=O)Nc3ccccc23)c(OC)c1

InChI

1S/C18H17NO4/c1-21-11-8-16(22-2)14(17(9-11)23-3)10-13-12-6-4-5-7-15(12)19-18(13)20/h4-10H,1-3H3,(H,19,20)/b13-10-

InChI key

JBJYTZXCZDNOJW-RAXLEYEMSA-N

Gene Information

Biochem/physiol Actions

Casein kinase 1 δ (CK1δ) and CK1 ε inhibitor.

Physical form

Product is a mixture of the Z- and E-isomers, with the predominant isomer expected to be E.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Marta Vázquez-Cedeira et al.
PloS one, 6(8), e23235-e23235 (2011-08-11)
Human vaccinia-related kinases (VRK1 and VRK2) are atypical active Ser-Thr kinases implicated in control of cell cycle entry, apoptosis and autophagy, and affect signalling by mitogen activated protein kinases (MAPK). The specific structural differences in VRK catalytic sites make them
Konstantinos Gkatzis et al.
eLife, 10 (2021-09-30)
Lung epithelial progenitors differentiate into alveolar type 1 (AT1) and type 2 (AT2) cells. These cells form the air-blood interface and secrete surfactant, respectively, and are essential for lung maturation and function. Current protocols to derive and culture alveolar cells

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service