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EMU092041

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Nr2f6

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CTCCCAGCTCTTCTTCATGCGCTTGGTGGGCAAGACACCCATCGAGACCCTCATCCGGGACATGCTTCTGTCAGGGAGCACCTTTAACTGGCCCTATGGCTCGGGCTAGTGATAGTCACCTTCCAGGACACACATGGAAACTGGGGCCTTGTGGGGACCCTGGGGATCAGGGCCCCAGCTTCTCTTTTGAGACTGATTTCTTTTTTTAAAGACTGTGAAATGTTTGTTTTGTTTTATTTTTTAAATAATCATGAAACCAAAAAGATTTGGATCTCCCTAGGCCTTGTCCTGGCAGACCTTCAACAGTCTGGAGCCAGCATGCTGGTGCCTCTGGTGTCATGGGTATCTGGAAAGGCCACTGCAGCTAGGCAGGAGTACTATGGGCCAGGAGGATCCCCTGGATACATGGTCCACGGAGGGCACCATGGGATGATGAAAACCTGGCCAAT

Ensembl | mouse accession no.

ENSMUSG00000002393

NCBI accession no.

NM_010150

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... Nr2f6(13864)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Victoria Klepsch et al.
Nature communications, 9(1), 1538-1538 (2018-04-20)
Analyzing mouse tumor models in vivo, human T cells ex vivo, and human lung cancer samples, we provide direct evidence that NR2F6 acts as an immune checkpoint. Genetic ablation of Nr2f6, particularly in combination with established cancer immune checkpoint blockade

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