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EHU060191

Sigma-Aldrich

MISSION® esiRNA

targeting human FBXO44

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CTCCTGACTTCGCCCTACTGCATGCAGCCAAATAAAAGGTGTGCCCAGTCTAACCTGTGCCCTGTGGTTTCTGGAAGGAAAGGCAGACTTTAGGTGGTCCTGCCTGGACCTGCAGATGGTACAATGGCATGGCTTCTGTCTAAGGTACAGAGGGGTTGGCATTTCAGGAACCAGGCCATCACAGAAACAGGTTCATGGGCAGACCCCTCAGTGAGCTGCAGGTATCTCACCTGGCAGCCGTCCAGTACTGCTGGCTTCCTCTGGAGGCCCAGCCACAGGCTGGGGTTGGGGTGTGTGGACATCTCTGGGCAGCTCTTGAGTCCACCTTGTGCCAGATCAGCAGTGCCACCCAGGCTCTGCCTCCTGGTGTTACTCTTTGCCAACAGCTTTACGGACATTGGATGAAGCCGAAGCATTTA

Ensembl | human accession no.

ENSG00000132879

NCBI accession no.

NM_183412

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... FBXO44(93611) , FBXO44(93611)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Jia Z Shen et al.
Cell, 184(2), 352-369 (2020-12-29)
Repetitive elements (REs) compose ∼50% of the human genome and are normally transcriptionally silenced, although the mechanism has remained elusive. Through an RNAi screen, we identified FBXO44 as an essential repressor of REs in cancer cells. FBXO44 bound H3K9me3-modified nucleosomes

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