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D9690

Sigma-Aldrich

β-Defensin 2 human

recombinant, expressed in E. coli, lyophilized powder (from 10 mM acetic acid)

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About This Item

MDL number:
MFCD01634440
UNSPSC Code:
12352202
NACRES:
NA.32

recombinant

expressed in E. coli

Quality Level

200

form

lyophilized powder (from 10 mM acetic acid)

mol wt

estimated mol wt 4.3 kDa

UniProt accession no.

O15263

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria
fungi
viruses

Mode of action

cell wall synthesis | interferes

storage temp.

−20°C

Gene Information

human ... DEFB4(1673)

Amino Acid Sequence

Gly-Ile-Gly-Asp-Pro-Val-Thr-Cys-Leu-Lys-Ser-Gly-Ala-Ile-Cys-His-Pro-Val-Phe-Cys-Pro-Arg-Arg-Tyr-Lys-Gln-Ile-Gly-Thr-Cys-Gly-Leu-Pro-Gly-Thr-Lys-Cys-Cys-Lys-Lys-Pro

General description

Chemical structure: peptide

Biochem/physiol Actions

A small cationic peptide which demonstrates anti-microbial activity and is expressed in keratinocytes and the epithelia of many organs.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Antimicrobial Peptides

With bacterial resistance and emerging infectious diseases becoming potential threats to humans, ribosomally synthesized antimicrobial peptides have become a promising focus area in antibiotic research.

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