C3617

Anti-Casein Kinase 2β antibody, Mouse monoclonal

clone 6D5, purified from hybridoma cell culture

• Synonym(s): Anti-CK2β
• MDL number: MFCD00675215
• UNSPSC Code: 12352203
• NACRES: NA.44

Properties

• biological source: mouse
• Quality Level: 200
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 6D5, monoclonal
• form: buffered aqueous solution
• mol wt: antigen ~30 kDa
• species reactivity: mouse, hamster, bovine, rat, human
• concentration: ~2 mg/mL
• technique(s): dot blot: suitable; indirect ELISA: suitable; microarray: suitable; western blot: 2-4 μg/mL using total cell extract of HepG2 cells
• isotype: IgG1
• UniProt accession no.: P67870
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... CSNK2B(1460) ; mouse ... Csnk2b(13001) ; rat ... Csnk2b(81650)

Description

General description

Casein Kinase 2 (CK2) is a ubiquitously expressed serine/threonine kinase that has been implicated in various cellular functions such as cell death, cell cycle regulation, and mRNA synthesis. This protein kinase comprises of two catalytic α subunits and two dimeric β subunits that associate to form a heterotetrameric enzyme complex.CK2 is also involved in regulating viral infections
Monoclonal Anti-Casein Kinase 2β antibody is specific for human, bovine, rat, mouse and hamster Casein Kinase 2β (approx. 30 kDa). The antibody epitope lies within amino-acids 123-127 of human CK2β.

Immunogen

recombinant human casein kinase 2β (CK2β). The antibody epitope resides within amino acids 123-127.

Application

Monoclonal Anti-Casein Kinase 2β antibody is suitable for use in indirect immunofluorescence (using A549 cells ). The product can also be used for western blot (2-4 μg/mL using total cell extract of HepG2 cells), microarray, dot blot and indirect ELISA.

Biochem/physiol Actions

Casein Kinase 2β encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha pr

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves