31995

Barbital

BioXtra, ≥99.0% (T)

• Synonym(s): 5,5-Diethyl-2,4,6(1H,3H,5H)-pyrimidinetrione, 5,5-Diethylbarbituric acid, Barbitone, Veronal
• Empirical Formula (Hill Notation): C₈H₁₂N₂O₃
• CAS Number: 57-44-3
• Molecular Weight: 184.19
• Beilstein: 163999
• EC Number: 200-331-2
• MDL number: MFCD00036212
• UNSPSC Code: 12352111
• PubChem Substance ID: 57648640
• NACRES: NA.21

Properties

• product line: BioXtra
• Quality Level: 200
• Assay: ≥99.0% (T)
• drug control: USDEA Schedule IV; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• ign. residue: ≤0.1% (as SO₄)
• loss: ≤0.5% loss on drying, 20 °C (HV)
• mp: 189-191 °C
• solubility: alcohol: soluble 1 gm in 14 ml; chloroform: soluble 1 gm in 75 ml; diethyl ether: soluble 1 gm in 35 ml; water: soluble 1 gm in 13 ml (boiling); water: soluble 1 gm in 130 ml; acetone: soluble; ethyl acetate: soluble; nitrobenzene: soluble; petroleum ether: soluble; pyridine: soluble
• anion traces: chloride (Cl^-): ≤500 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• cation traces: Ca: ≤50 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤200 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• SMILES string: CCC1(CC)C(=O)NC(=O)NC1=O
• InChI: 1S/C8H12N2O3/c1-3-8(4-2)5(11)9-7(13)10-6(8)12/h3-4H2,1-2H3,(H2,9,10,11,12,13)
• InChI key: FTOAOBMCPZCFFF-UHFFFAOYSA-N

Description

Application

Barbital has been used as an assay buffer for determining the carbonic anhydrase activity. It has also been used for rocket immunoelectrophoresis.

Biochem/physiol Actions

Barbital also referred to as 5,5-Diethylbarbituric acid, Barbitone or Veronal is a sedative/hypnotic (sleeping aid). It stimulates the development of tumors in rats treated with a sub-effective dose of N-bis(2-hydroxypropyl)nitrosamine (DHPN).

Sedative/hypnotic

Other Notes

Sales restrictions may apply

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves