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Key Documents

11813

Sigma-Aldrich

Potassium cyanide

technical, ≥96%

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About This Item

Linear Formula:
KCN
CAS Number:
Molecular Weight:
65.12
Beilstein:
3593645
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
SB.54

grade

technical

Assay

≥96%

form

solid

pH

11.5 (20 °C, 20 g/L)

mp

634 °C (lit.)

cation traces

Na: ≤5000 mg/kg

SMILES string

[K]C#N

InChI

1S/CN.K/c1-2;

InChI key

YUZRZFQHUCKACF-UHFFFAOYSA-N

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Application


  • Characterization, antimicrobial and antitumor activity of superoxide dismutase extracted from Egyptian honeybee venom (Apis mellifera lamarckii).: This study explores the extraction and characterization of superoxide dismutase from honeybee venom, highlighting its antimicrobial and antitumor properties. Potassium cyanide was used in the biochemical analysis to understand the enzyme′s activity and stability (Abdel-Monsef et al., 2023).

  • Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib.: This research investigates the metabolic pathways of masitinib, focusing on the role of cytochromes P450. Potassium cyanide is used to inhibit specific enzymatic activities during the analysis, providing insights into drug metabolism and potential toxicological impacts (Latham et al., 2022).

  • Profiling of in vivo, in vitro and reactive zorifertinib metabolites using liquid chromatography ion trap mass spectrometry.: The study details the metabolic profiling of zorifertinib using advanced chromatographic techniques. Potassium cyanide serves as an analytical reagent to assess the stability and reactivity of various metabolites (Al-Shakliah et al., 2022).

  • Structural and Biochemical Characterization of a Dye-Decolorizing Peroxidase from Dictyostelium discoideum.: The research characterizes a peroxidase enzyme from Dictyostelium discoideum, utilizing potassium cyanide in the enzymatic assays to inhibit specific reactions and better understand the enzyme′s functionality (Rai et al., 2021).

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Met. Corr. 1 - STOT RE 1

Target Organs

Thyroid

Supplementary Hazards

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Eagleson M.
Concise Encyclopedia Chemistry, 887-887 (1994)
Catalytic asymmetric synthesis of O-acetylcyanohydrins from potassium cyanide, acetic anhydride, and aldehydes, promoted by chiral salen complexes of titanium (IV) and vanadium (V).
Belokon YN, et al.
Helvetica Chimica Acta, 85(10), 3301-3312 (2002)
Reaction of the Methiodide of N, N-Dimethylaminomethylferrocene with Potassium Cyanide to Form Ferrocylacetonitrile1.
Lednicer D, et al.
The Journal of Organic Chemistry, 23(5), 653-655 (1958)
The determination of amino-acids with ninhydrin.
Yemm EW, et al.
Analyst, 80(948), 209-214 (1955)
Xiao-Zhang Yu et al.
Journal of hazardous materials, 225-226, 190-194 (2012-05-29)
A study was conducted to investigate activities of nitrate reductase (NR) and glutamine synthetase (GS) in plants during cyanide metabolism. Young rice seedlings (Oryza sativa L. cv. XZX 45) were grown in the nutrient solutions containing KNO(3) or NH(4)Cl and

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