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Key Documents

AB5644P

Sigma-Aldrich

Anti-Fatty Acid Amide Hydrolase Antibody

Chemicon®, from rabbit

Synonym(s):

FAAH

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, rat

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... FAAH(2166)

Specificity

Recognizes human Fatty Acid Amide Hydrolase (FAAH). The immunogen shows no significant sequence homology with other hydrolases

SPECIES REACTIVITIES: The immunogen peptide is 100% conserved in rat, 94% in mouse and porcine and 58% in chicken. Reactivity with other species has not been confirmed.

Immunogen

A 17 amino acid peptide sequence near the N-terminus of human FAAH (Patricelli et al. 1998; Maccarone et al. 1998; Cravatt et al. 1996; Giang et al. 1997; Thomas et al. 1997; Wan et al. 1998).

Application

This Anti-Fatty Acid Amide Hydrolase Antibody is validated for use in ELISA, WB for the detection of Fatty Acid Amide Hydrolase.
Western blot: 1-10 μg/mL using ECL.

ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide (Catalog Number AG376) per well.

Optimal working dilutions must be determined by the end user.

Physical form

Affinity purified immunoglobulin. Liquid in 100 mM Tris, pH 7.5, containing 0.2% BSA and 0.05% sodium azide.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Endocannabinoids in the intact retina: 3 H-anandamide uptake, fatty acid amide hydrolase immunoreactivity and hydrolysis of anandamide.
Sherrye T Glaser, Dale G Deutsch, Keith M Studholme, Sarah Zimov, Stephen Yazulla
Visual Neuroscience null
Tania Aguado et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 19(12), 1704-1706 (2005-07-23)
The discovery of multipotent neural progenitor (NP) cells has provided strong support for the existence of neurogenesis in the adult brain. However, the signals controlling NP proliferation remain elusive. Endocannabinoids, the endogenous counterparts of marijuana-derived cannabinoids, act as neuromodulators via
Tania Aguado et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 26(5), 1551-1561 (2006-02-03)
Endocannabinoids exert an important neuromodulatory role via presynaptic cannabinoid CB1 receptors and may also participate in the control of neural cell death and survival. The function of the endocannabinoid system has been extensively studied in differentiated neurons, but its potential
Cristina Blázquez et al.
Brain : a journal of neurology, 134(Pt 1), 119-136 (2010-10-12)
Endocannabinoids act as neuromodulatory and neuroprotective cues by engaging type 1 cannabinoid receptors. These receptors are highly abundant in the basal ganglia and play a pivotal role in the control of motor behaviour. An early downregulation of type 1 cannabinoid

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