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8.52100

Sigma-Aldrich

Fmoc-Lys(biotinyl-ε-aminocaproyl)-OH

Novabiochem®

Synonym(s):

Fmoc-Lys(biotinyl-ε-aminocaproyl)-OH, N-α-Fmoc-N-ε-(biotinylcaproyl)-L-lysine

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About This Item

Empirical Formula (Hill Notation):
C37H49N5O7S
CAS Number:
Molecular Weight:
707.88
UNSPSC Code:
12352209
NACRES:
NA.22

Quality Level

product line

Novabiochem®

Assay

≥90.0% (HPLC)
≥98% (TLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

biotin

storage temp.

2-30°C

General description

A modified lysine derivative for the preparation of biotin-labeled peptides by Fmoc SPPS, in which the biotin is separated from the lysine side-chain by a 6 C-atom spacer.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Biotinylation Reagents for Peptide Synthesis

Linkage

Replaces: 04-12-1243

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): +11.5 - +16.0 °
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 90.0 % (a/a)
Solubility (100mg in 10 ml DMF): clearly soluble
This product can obtain up to 10% DMF in order to assure an ideal solubility.

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Related Content

Biotin-labelled peptides have many important applications in immunology and histochemistry, such as affinity purification and FRET-based flow cytometry, solid-phase immunoassays, and receptor localization, that exploit the high affinity of streptavidin and avidin for biotin.

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