form
lyophilized
Quality Level
specific activity
≥1800 NIH units/mg protein
≥50 NIH units/mg dry wt
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
0.05 M NaCl: ≤2000 NIH units/mL
water: >2000 NIH units/mL
shipped in
ambient
storage temp.
−20°C
General description
Native, bovine thrombin. Key enzyme in the coagulation cascade. Converts fibrinogen into fibrin and activates factor XIII, which cross-links and stabilizes the fibrin polymer. Has a pH of 6.0-7.5 in a 7% solution.
Native, bovine thrombin. Key enzyme that activates factor XIII and converts fibronogen into fibrin.
Packaging
Please refer to vial label for lot-specific concentration.
Warning
Toxicity: Harmful (C)
Unit Definition
One unit is determined by comparison with a standard curve prepared using the Bureau of Biologics standard thrombin.
Physical form
Lyophilized from 50 mM Sodium Citrate, 0.2 M NaCl, 0.1% PEG-8000, pH 6.5.
Reconstitution
Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 2 months at -70°C.
From Catalog:
Desc. Field- added "Key enzyme that activates factor XIII and converts fibronogen into fibrin."
From Catalog:
Desc. Field- added "Key enzyme that activates factor XIII and converts fibronogen into fibrin."
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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