233483

Coagulation Factor XIa, Human Plasma

Coagulation Factor XIa, Human Plasma, is a native coagulation factor XIa prepared from homogeneous Factor XI by activation with human Factor XIIa. Factor XIIa is removed after activation.

• UNSPSC Code: 12352202

Properties

• Quality Level: 100
• form: liquid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• shipped in: wet ice
• storage temp.: −70°C

Description

General description

Native coagulation factor XIa from human plasma prepared from homogeneous Factor XI by activation with human Factor XIIa. Factor XIIa is removed after activation. In vivo, Factor XI is activated to Factor XIa via Factor XIIa and High Molecular Weight Kininogen (Cat. No. 422686). Factor XIa activates Factor IX to Factor IXa in a reaction that does not require membrane surfaces.

Native coagulation factor XIa from human plasma prepared from homogeneous Factor XI by activation with human Factor XIIa. Factor XIIa is removed after activation. In vivo, Factor XI is activated to Factor XIa via Factor XIIa and High Molecular Weight Kininogen (Cat. No. 422686). Factor XIa activates Factor IX to Factor IXa in a reaction that does not require membrane surfaces.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Analysis Note

homogeneous by SDS-PAGE

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable