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840072P

Avanti

Soy Lyso PC

Avanti Research™ - A Croda Brand 840072P, powder

Synonym(s):

L-α-lysophosphatidylcholine (Soy)

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About This Item

CAS Number:
97281-38-4
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

form

powder

packaging

pkg of 2 × 100 mg (840072P-200mg)
pkg of 1 × 25 mg (840072P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 840072P

lipid type

phospholipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCCCCC)=O

InChI

1S/C24H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)30-21-23(26)22-32-33(28,29)31-20-19-25(2,3)4/h23,26H,5-22H2,1-4H3/t23-/m1/s1

InChI key

ASWBNKHCZGQVJV-HSZRJFAPSA-N

General description

Lyso Phosphatidylcholine (LPC) or lysolecithin is a minor phospholipid in plasma (8-12%) and cellular membranes (<3%).

Application

Soy Lyso PC has been used in the synthesis of 15-methylhexadecanoic acid (15-MHDA) and glycerophospholipids.

Biochem/physiol Actions

Soy Lyso phosphocholine or phosphotidylcholine (PC) is among the other lipids present in soybean lecithin. Lysophosphatidylcholine (LPC) is a bioactive proinflammatory lipid. It is generated during pathological activities and is implicated in atherosclerosis and inflammatory diseases. LPC modifies the functions of numerous cell-types, including smooth muscle cells, endothelial cells, macrophages, monocytes, and T-cells. LPC activates several second messengers and is involved in signal transduction mechanisms.

Packaging

5 mL Clear Glass Sealed Ampule (840072P-200mg)
5 mL Clear Glass Sealed Ampule (840072P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sigma-Aldrich

519235

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The use of natural and synthetic phospholipids as pharmaceutical excipients
van Hoogevest P and Wendel A
European Journal of Lipid Science and Technology, 116(9), 1088-1107 (2014)
Lysophosphatidylcholine (lysolecithin) and its synthetic analogues. Immunemodulating and other biologic effects
Munder, PG and Modolell, M and Andreesen, Reinhard and Weltzien, HU and Westphal, O
Seminars in Immunopathology, 2(2), 187-203 (1979)
Thomas Linemann et al.
Pharmaceutics, 5(2), 246-260 (2013-12-05)
The aim of the present study was to evaluate the transfection potential of chitosan-coated, green-fluorescent magnetic nanoparticles (MNPs) (chi-MNPs) after encapsulation inside polyethylglycol (PEG)ylated liposomes that produced lipid-encapsulated chitosan-coated MNPs (lip-MNPs), and also to evaluate how these particles would distribute
High-Throughput Plasma Lipidomics: Detailed Mapping of the Associations with Cardiometabolic Risk Factors
Huynh K, et al.
Cell Chemical Biology, 26(1), 71-84 (2019)
Role of lysophosphatidylcholine (LPC) in atherosclerosis
Matsumoto T, et al.
Current Medicinal Chemistry, 14(30), 3209-3220 (2007)

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