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T24201

Sigma-Aldrich

Tetramethylthiuram disulfide

97%

Synonym(s):

Bis(dimethylthiocarbamoyl) disulfide, Bis(dimethylthiocarbamyl) disulfide, Thiram

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About This Item

Linear Formula:
(CH3)2NCSS2CSN(CH3)2
CAS Number:
137-26-8
Molecular Weight:
240.43
Beilstein:
1725821
EC Number:
205-286-2
MDL number:
MFCD00008325
UNSPSC Code:
12352100
PubChem Substance ID:
24900038
NACRES:
NA.22

Assay

97%

autoignition temp.

316 °F

mp

156-158 °C (lit.)

SMILES string

CN(C)C(=S)SSC(=S)N(C)C

InChI

1S/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3

InChI key

KUAZQDVKQLNFPE-UHFFFAOYSA-N

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Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral

Target Organs

Liver

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Weiwei Deng et al.
PloS one, 10(6), e0129781-e0129781 (2015-06-13)
The plant circadian clock is an internal timekeeper that coordinates biological processes with daily changes in the external environment. The transcript levels of clock genes, which oscillate to control circadian outputs, were examined during early seedling development in barley (Hordeum
Toxicology of thiram (tetramethylthiuram disulfide): a review.
R R Dalvi
Veterinary and human toxicology, 30(5), 480-482 (1988-10-01)
Vaneet Kumar Sharma et al.
Journal of environmental monitoring : JEM, 5(5), 717-723 (2003-11-01)
In this review a brief introduction to thiram (tetramethylthiuram disulfide; TMTD) pesticide has been given along with other applications. All the important methods available are systematically arranged and are listed under various techniques. Some of these methods have been applied
Coco N Kapanda et al.
Journal of medicinal chemistry, 52(22), 7310-7314 (2009-11-04)
Monoglyceride lipase (MGL) inhibition may offer an approach in treating diseases in which higher 2-arachidonoyglycerol activity would be beneficial. We report here the synthesis and pharmacological evaluation of bis(dialkylaminethiocarbonyl)disulfide derivatives as irreversible MGL inhibitors. Inhibition occurs through interactions with MGL
Alfredo Santovito et al.
Drug and chemical toxicology, 35(3), 347-351 (2012-02-01)
In vitro effects of different concentrations of Thiram were tested on human lymphocytes to determine, by means of the chromosome aberrations (CAs) assay, whether this fungicide could induce clastogenic damage. Evidences of the effect of Thiram on human lymphocytes were
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