E51406

1-Ethynyl-1-cyclohexanol

≥99%

• Synonym(s): (1-Hydroxycyclohexyl)acetylene, (1-Hydroxycyclohexyl)ethyne, 1-Ethynyl-1-hydroxycyclohexane, 1-Ethynylcyclohexanal, 1-Ethynylcyclohexanol, 1-Hydroxy-1-ethynylcyclohexane, Ethynylcyclohexanol
• Linear Formula: HC≡CC₆H₁₀OH
• CAS Number: 78-27-3
• Molecular Weight: 124.18
• Beilstein: 471404
• EC Number: 201-100-9
• MDL number: MFCD00003858
• UNSPSC Code: 12352100
• PubChem Substance ID: 24894607
• NACRES: NA.22

Properties

• vapor pressure: <1 mmHg ( 20 °C)
• Quality Level: 200
• Assay: ≥99%
• bp: 180 °C (lit.)
• mp: 30-33 °C (lit.)
• density: 0.967 g/mL at 25 °C (lit.)
• SMILES string: OC1(CCCCC1)C#C
• InChI: 1S/C8H12O/c1-2-8(9)6-4-3-5-7-8/h1,9H,3-7H2
• InChI key: QYLFHLNFIHBCPR-UHFFFAOYSA-N

Description

Application

1-Ethynyl-1-cyclohexanol (ECHO) can undergo acetylation in the presence of a catalytic amount of ruthenium chloride at room temperature. It can be used to synthesize novel organotellurium(IV) compounds with potent inhibitory activity towards Cathepsin B. The polymerization of ECHO by transition metal catalysts leads to the formation of poly(ECHO). It can also react with transition metal hydride complexes to form vinyl derivatives by inserting into the M-H bonds.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H302,H311,H315,H319
• Precautionary Statements: P264 - P270 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 1
• Flash Point(F): 163.4 °F - closed cup
• Flash Point(C): 73 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves