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B4638

Sigma-Aldrich

Betahistine dihydrochloride

≥98%

Synonym(s):

Methyl[2-(2-pyridyl)ethyl]amine dihydrochloride

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About This Item

Empirical Formula (Hill Notation):
C8H12N2 · 2HCl
CAS Number:
5579-84-0
Molecular Weight:
209.12
EC Number:
226-966-5
MDL number:
MFCD00012813
UNSPSC Code:
12352100
PubChem Substance ID:
57653935
NACRES:
NA.22

Assay

≥98%

form

powder

SMILES string

Cl.CNCCc1ccccn1

InChI

1S/C8H12N2.2ClH/c1-9-7-5-8-4-2-3-6-10-8;;/h2-4,6,9H,5,7H2,1H3;2*1H

InChI key

XVDFMHARQUBJRE-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269) , HRH3(11255)

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Enis Alpin Guneri et al.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 146(1), 104-108 (2011-08-20)
The purpose of this study is to evaluate the effects of betahistine in addition to Epley maneuver on the quality of life of patients with posterior semicircular canal benign paroxysmal positional vertigo (BPPV) of the canalithiasis type. Double-blind, randomized, controlled
Burkhard Franz et al.
Acta oto-laryngologica, 131(11), 1155-1159 (2011-09-13)
Betahistine dihydrochloride, a drug used widely in the systemic treatment of balance disorders such as Ménière's disease, was found to improve eustachian tube function when applied topically in the nasopharynx of rats. The study tested the effect of betahistine, a
T Y Kew et al.
The Journal of laryngology and otology, 126(1), 66-71 (2011-08-27)
We report an extremely rare case of duplication of the internal auditory canal associated with dysfunction of both the facial and vestibulocochlear nerves. We also review the literature regarding the integrity of the facial and vestibulocochlear nerves in such cases.
Maurício Malavasi Ganança et al.
Brazilian journal of otorhinolaryngology, 77(4), 499-503 (2011-08-24)
Betahistine is a medicine used to treat vestibular disorders that has also been used to treat tinnitus. To assess the effects of betahistine on tinnitus in patients with vestibular disorders. Retrospective data were collected from patient records for individuals presenting
Fritz Ihler et al.
PloS one, 7(6), e39086-e39086 (2012-06-30)
Betahistine is a histamine H(1)-receptor agonist and H(3)-receptor antagonist that is administered to treat Menière's disease. Despite widespread use, its pharmacological mode of action has not been entirely elucidated. This study investigated the effect of betahistine on guinea pigs at
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