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Sigma-Aldrich

Poly(ethylene oxide)

average Mv ~900,000 (nominal), powder

Synonym(s):

Polyethylene oxide, PEO

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About This Item

Linear Formula:
(-CH2CH2O-)n
CAS Number:
25322-68-3
MDL number:
MFCD00081839
UNSPSC Code:
12352104
PubChem Substance ID:
24851381
NACRES:
NA.23

form

powder

Quality Level

200

mol wt

average Mv ~900,000 (nominal)

contains

200-500 ppm BHT as inhibitor

viscosity

8,800-17,600 cP, 5 % in H2O(25 °C, Brookfield)(lit.)

transition temp

Tm 65 °C

density

1.21 g/mL at 25 °C

functional group

hydroxyl

SMILES string

[H]OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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General description

Poly(ethylene oxide) is a synthetic hydrophilicpolymer available in a number of molecular weights. It can be obtained by thering-opening polymerization of ethylene oxide. This biocompatible polymer can be widely used in the field of biomedical research,tissue engineering and surface functionalization.

Application

PEO can be used to prepare polymer electrolyte systems for energy storage and conversion devices due its low glass transition temperature and ability to form complex with many alkaline salts.

Owing to its hydration and swelling properties, it is widely used as a precursor to prepare block copolymer micelles for selective drug and gene delivery.

Itcan also be used to fabricate nanofibrous membranes for the adsorption of heavymetal ions.

Features and Benefits

  • Excellent polymer chain flexibility
  • Low toxicity
  • High solvation power
  • Lowglass transition temperature

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Peritendinous adhesion is a major complication after tendon injury and the subsequent repairs or reconstructions. The degree of adhesion can be reduced by the interposition of a membranous barrier between the traumatized tendon and the surrounding tissue. In the present
Daniel O'Brien et al.
Biomedical microdevices, 21(3), 53-53 (2019-06-17)
The biocompatible and biodegradable polymer poly(glycerol sebacate), or PGS, is a rubber-like material that finds use in several biomedical applications. PGS is often cast into a mold to form desired structures; alternatively, blending PGS with other reinforcing polymers produces viscous
D D Smyth et al.
Cardiovascular drugs and therapy, 4(1), 297-300 (1990-02-01)
Previous studies have demonstrated that Separan AP-30, a drag-reducing polymer, significantly decreased the formation of atherosclerotic plaques in rabbits fed a high-cholesterol diet. Furthermore, Separan AP-273, a polymer similar to but longer than Separan AP-30, markedly increased cardiac output in
M Patel Geeta et al.
Current drug delivery, 6(2), 159-165 (2009-05-20)
Carbamazepine indicated for the control of epilepsy, undergoes extensive hepatic first-pass metabolism after oral administration. A vaginal dosage form of carbamazepine is not commercially available. Conventional suppository having poor retention in the vaginal tract, as they are removed in a
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
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