103594

1-Nitronaphthalene

99%

• Empirical Formula (Hill Notation): C₁₀H₇NO₂
• CAS Number: 86-57-7
• Molecular Weight: 173.17
• Beilstein: 1867714
• EC Number: 201-684-5
• MDL number: MFCD00003913
• UNSPSC Code: 12352100
• PubChem Substance ID: 24846612
• NACRES: NA.22

Properties

• Assay: 99%
• form: solid
• bp: 304 °C (lit.)
• mp: 53-57 °C (lit.)
• solubility: H₂O: insoluble; alcohol: soluble; carbon disulfide: freely soluble; chloroform: soluble; diethyl ether: freely soluble
• density: 1.223 g/mL at 25 °C (lit.)
• SMILES string: [O-][N+](=O)c1cccc2ccccc12
• InChI: 1S/C10H7NO2/c12-11(13)10-7-3-5-8-4-1-2-6-9(8)10/h1-7H
• InChI key: RJKGJBPXVHTNJL-UHFFFAOYSA-N

Description

General description

1-Nitronaphthalene is a mutagenic nitroaromatic compound present in diesel exhaust and it causes acute liver and lung toxicity in rodents. 1-Nitronaphthalene is a cytochrome P450-bioactivated, nonciliated bronchiolar epithelial (Clara) cell cytotoxicant .

Application

1-Nitronaphthalene was used to study excited state dynamics of 1-nitropthalene in nonpolar, aprotic and protic solvents.

Biochem/physiol Actions

1-Nitronaphthalene binds covalently to protein and forms adducts in the rat airway epithelium in vivo.

Safety Information

• Pictograms: GHS02,GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H228,H302,H411
• Precautionary Statements: P210 - P240 - P241 - P264 - P273 - P301 + P312
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Flam. Sol. 2
• Storage Class Code: 4.1B - Flammable solid hazardous materials
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves