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Merck

LC/MS (TOF) Analysis of Opioids and Opiate-Dependence Management Drugs on Ascentis® Express HILIC

LC/MS (TOF) Analysis of Opioids and Opiate-Dependence Management Drugs on Ascentis® Express HILIC application for HPLC

CONDITIONS

column

Ascentis Express HILIC, 5 cm x 2.1 mm I.D., 2.7 μm particles (53934-U)

mobile phase

2 mM ammonium formate in 90:10 (v:v) acetonitrile:water

flow rate

0.3 mL/min

column temp.

55 °C

detector

TOF/MS

injection

2 μL

sample

400 ng/mL in acetonitrile

Description

Remarque sur l'analyse

The rapid analysis by HPLC with TOF-MS detection of seven opioids is shown here using an Ascentis Express HILIC column. Cerilliant CRMs were used to ensure reliable MS identification and quantification.

Informations légales

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany