Accéder au contenu
Merck
  • Enriching the Housing Environment for Mice Enhances Their NK Cell Antitumor Immunity via Sympathetic Nerve-Dependent Regulation of NKG2D and CCR5.

Enriching the Housing Environment for Mice Enhances Their NK Cell Antitumor Immunity via Sympathetic Nerve-Dependent Regulation of NKG2D and CCR5.

Cancer research (2017-01-14)
Yanfang Song, Yu Gan, Qing Wang, Zihong Meng, Guohua Li, Yuling Shen, Yufeng Wu, Peiying Li, Ming Yao, Jianren Gu, Hong Tu
RÉSUMÉ

Mice housed in an enriched environment display a tumor-resistant phenotype due to eustress stimulation. However, the mechanisms underlying enriched environment-induced protection against cancers remain largely unexplained. In this study, we observed a significant antitumor effect induced by enriched environment in murine pancreatic cancer and lung cancer models. This effect remained intact in T/B lymphocyte-deficient Rag1

MATÉRIAUX
Référence du produit
Marque
Description du produit

Sigma-Aldrich
3,7-Diacetyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane, 97%