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Cutaneous necrobiotic xanthogranuloma (NXG)--successfully treated with low dose chlorambucil.

European journal of dermatology : EJD (2001-08-30)
S Machado, R Alves, M Lima, I Leal, A Massa
RÉSUMÉ

We report a case of necrobiotic xanthogranuloma in a 51 year-old white male patient presenting with a 6-year history of multiple indurated violaceous nodules and plaques involving the eyelids, trunk and extremities. He had an associated paraproteinemia (Ig G lambda), elevated sedimentation rate, cryoglobulinemia and hypocomplementemia. No extracutaneous involvement was detected. He was successfully treated with chlorambucil (2 mg/d for 7 months), leading to disappearance of all skin lesions.

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Chlorambucil
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Chlorambucil, European Pharmacopoeia (EP) Reference Standard
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Chlorambucil for system suitability, European Pharmacopoeia (EP) Reference Standard
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