Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation.

Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation.

Science advances (2021-09-16)

Ana Tapia-Abellán, Diego Angosto-Bazarra, Cristina Alarcón-Vila, María C Baños, Iva Hafner-Bratkovič, Baldomero Oliva, Pablo Pelegrín

PMID34524838

RÉSUMÉ

[Figure: see text].

MATÉRIAUX

Référence du produit

Marque

Description du produit

400015

Sigma-Aldrich

Caspase-1 Inhibitor IV, The Caspase-1 Inhibitor IV, also referenced under CAS 154674-81-4, controls the biological activity of Caspase-1. This small molecule/inhibitor is primarily used for Cancer applications.