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1078733

USP

Bupropion hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

(±)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride

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About This Item

Formule empirique (notation de Hill):
C13H18ClNO · HCl
Numéro CAS:
31677-93-7
Poids moléculaire :
276.20
Numéro MDL:
MFCD00055209
Code UNSPSC :
41116107
ID de substance PubChem :
329749161
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

bupropion

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

Cl[H].CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1

InChI

1S/C13H18ClNO.ClH/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10;/h5-9,15H,1-4H3;1H

Clé InChI

HEYVINCGKDONRU-UHFFFAOYSA-N

Informations sur le gène

human ... SLC6A2(6530) , SLC6A3(6531)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Bupropion hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Bupropion Hydrochloride Extended-Release Tablets
  • Bupropion Hydrochloride Tablets

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

1078744

Bupropion Hydrochloride Related Compound A, United States Pharmacopeia (USP) Reference Standard

1078755

Bupropion Hydrochloride Related Compound B, United States Pharmacopeia (USP) Reference Standard

1078766

Bupropion Hydrochloride Related Compound C, United States Pharmacopeia (USP) Reference Standard

1078799

Bupropion Hydrochloride Related Compound F, United States Pharmacopeia (USP) Reference Standard

1078846

Bupropion hydrobromide, United States Pharmacopeia (USP) Reference Standard

1112299

3-Chlorobenzoic acid, United States Pharmacopeia (USP) Reference Standard

PHR1744

3-Chlorobenzoic acid, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1752

Bupropion Hydrochloride Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1753

Bupropion Hydrochloride Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1755

Bupropion Related Compound F, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1754

Bupropion Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

1078857

Bupropion Related Compound G, United States Pharmacopeia (USP) Reference Standard

1117020

Chloropropiophenone, United States Pharmacopeia (USP) Reference Standard

PHR3178

Bupropion Hydrobromide, pharmaceutical secondary standard, certified reference material

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Conseils de prudence

P301 + P312 + P330

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Sergios Charntikov et al.
Neuropharmacology, 86, 181-191 (2014-08-01)
Bupropion is an atypical antidepressant that increases long-term quit rates of tobacco smokers. A better understanding of the relation between nicotine and this first-line medication may provide insight into improving treatment. For all experiments, rats first had nicotine (0.4 mg base/kg)
R L Dufresne et al.
Drug intelligence & clinical pharmacy, 18(12), 957-964 (1984-12-01)
Bupropion is a trimethylated monocyclic phenylaminoketone that is an effective antidepressant in humans. It neither is sedating, anticholinergic, nor cardiotoxic. Its mechanism of action may be related to dopamine, but remains uncertain at this time. Clinical trials comparing bupropion 300-750
Marlene P Freeman
The American journal of psychiatry, 171(7), 723-728 (2014-07-02)
Attention deficit hyperactivity disorder (ADHD) has been increasingly recognized and treated in children and adults in recent years. As a result, a growing number of women enter their reproductive years treated with medication for ADHD or are diagnosed and start
S H Preskorn et al.
Pharmacotherapy, 4(1), 20-34 (1984-01-01)
Bupropion hydrochloride is a new antidepressant that differs clinically and pharmacologically from the tricyclic antidepressants and the monoamine oxidase inhibitors. Pharmacokinetically, bupropion is an intermediate-lived drug with a half-life of about 12 hours. Its antidepressant activity in man has been
Theresa M Winhusen et al.
The Journal of clinical psychiatry, 75(4), 336-343 (2013-12-19)
To evaluate the impact of concurrent treatments for substance use disorder and nicotine-dependence for stimulant-dependent patients. A randomized, 10-week trial with follow-up at 3 and 6 months after smoking quit date conducted at 12 substance use disorder treatment programs between
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