UBB
ubiquitin B
Synonymes:
Espèce(s):
Human UBB (7314), Mouse Ubb (22187), Rat Ubb (192255), cow UBB (281370), naked mole-rat Ubb (101702552), domestic guinea pig Ubb (100722422), Zebrafish ubb (550134), chicken UBB (396190), Horse UBB (100049794), domestic cat UBB (101091319)
ID UniProtKB:
ID du gène:
- Human(7314) Summary: This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq, Jul 2008]
- Mouse(22187) ubiquitin B
- Rat(192255) ubiquitin B
- cow(281370) ubiquitin B
- naked mole-rat(101702552) ubiquitin B
- domestic guinea pig(100722422) ubiquitin B
- Zebrafish(550134) ubiquitin B
- chicken(396190) ubiquitin B
- Horse(100049794) ubiquitin B
- domestic cat(101091319) ubiquitin B
- dog(479513) ubiquitin B
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anticorps anti-phospho-ubiquitine (Ser65), from rabbit, purified by affinity chromatography,
Espèces réactives
bovine, guinea pig, hamster, horse, human, mouse, nonhuman primates, rat, sheep
Application
immunocytochemistry
western blot
western blot
Anticorps anti-ubiquitine (pan), clone 2G7B8, clone 2G7B8, from mouse,
Espèces réactives
human
Application
western blot
Anti-Ubiquitin Lys63 Antibody, clone HWA4C4 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
ELISA
affinity binding assay
western blot
affinity binding assay
western blot
Anti-Ubiquitin Rabbit pAb, liquid, Calbiochem®,
Espèces réactives
drosophila, e. coli, bovine, canine, chicken, frog, guinea pig, hamster, human, monkey, mouse, rabbit, rat, sheep, yeast
Application
Anti-phospho-Ubiquitin (Ser57), ,
Espèces réactives
chimpanzee, hamster, human, mouse, rat
Application
affinity binding assay
western blot
western blot