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Merck

TNFRSF18

tumor necrosis factor receptor superfamily, member 18

Synonymes:
AITR, CD357, GITR, GITR-D
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(8784) Summary: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
  • Mouse(21936) tumor necrosis factor receptor superfamily, member 18
  • Rat(500598) tumor necrosis factor receptor superfamily, member 18
  • Zebrafish(571217) tumor necrosis factor receptor superfamily, member 18
  • domestic cat(101083251) tumor necrosis factor receptor superfamily, member 18
  • dog(606971) tumor necrosis factor receptor superfamily, member 18
  • chicken(419424) tumor necrosis factor receptor superfamily, member 18
  • naked mole-rat(101715065) tumor necrosis factor receptor superfamily, member 18
  • domestic guinea pig(100715459) tumor necrosis factor receptor superfamily, member 18
  • cow(516256) tumor necrosis factor receptor superfamily, member 18
  • sheep(101108672) tumor necrosis factor receptor superfamily, member 18

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ELISA

Référence du produit
Description
Espèce(s)
Human GITR / TNFRSF18 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human
Human GITR / TNFRSF18 ELISA Kit, for cell and tissue lysates,
Espèce(s)
human
Mouse Tnfrsf18 ELISA Kit, ,
Espèce(s)
mouse

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-TNFRSF18 (soluble form) Antibody, clone T10P2H9*B9, clone T10P2H9*B9, from mouse,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-hGITR Antibody, clone 108-17, clone 108-17, from mouse,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-TNFRSF18 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Monoclonal Anti-TNFRSF18 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL7787, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
human
Application
western blot
Anti-TNFRSF18 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse
Application
western blot

Proteins

Référence du produit
Description
Espèce(s)
CD40, FC Fusion, recombinant, expressed in HEK 293 cells,
Espèce(s)
human
GITR (CD357), FC Fusion, Biotin Labeled, recombinant, expressed in HEK 293 cells,
Espèce(s)
human
GITR (CD357), FC Fusion, recombinant, expressed in HEK 293 cells,
Espèce(s)
human