STAT5B
signal transducer and activator of transcription 5B
Synonymes:
STAT5
Espèce(s):
Human STAT5B (6777), Mouse Stat5b (20851), Rat Stat5b (25126), domestic guinea pig Stat5b (100716532), naked mole-rat Stat5b (101722721), cow STAT5B (282376), sheep STAT5B (101122961), chicken STAT5B (395556), domestic cat STAT5B (101090663), dog STAT5B (490969)
ID UniProtKB:
ID du gène:
- Human(6777) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
- Mouse(20851) signal transducer and activator of transcription 5B
- Rat(25126) signal transducer and activator of transcription 5B
- domestic guinea pig(100716532) signal transducer and activator of transcription 5B
- naked mole-rat(101722721) signal transducer and activator of transcription 5B
- cow(282376) signal transducer and activator of transcription 5B
- sheep(101122961) signal transducer and activator of transcription 5B
- chicken(395556) signal transducer and activator of transcription 5B
- domestic cat(101090663) signal transducer and activator of transcription 5B
- dog(490969) signal transducer and activator of transcription 5B
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ELISA
Référence du produit
Description
Espèce(s)
Cell-Based ELISA for detecting phospho-STAT5 (pTyr694) in cultured cell lines, 96 assays,
Espèce(s)
human
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-STAT5B Antibody, Upstate®, from rabbit,
Espèces réactives
human, mouse
Application
western blot
Anti-acetyl STAT5B (Lys701) Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
human
Application
dot blot
western blot
western blot
Anti-STAT5B (ab2) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
dog, horse, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-STAT5B Antibody, clone 2G13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
bovine, feline, human, monkey, porcine, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
ANTI-STAT5B antibody produced in mouse, clone 2D1, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Proteins
Référence du produit
Description
Espèce(s)