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Merck

PADI1

peptidyl arginine deiminase, type I

Synonymes:
HPAD10, PAD1, PDI, PDI1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(29943) Summary: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
  • Mouse(18599) peptidyl arginine deiminase, type I
  • Rat(54282) peptidyl arginine deiminase, type I
  • sheep(101108201) peptidyl arginine deiminase, type I
  • domestic guinea pig(100728246) peptidyl arginine deiminase, type I
  • naked mole-rat(101722077) peptidyl arginine deiminase, type I
  • chicken(428171) peptidyl arginine deiminase, type I
  • cow(618224) peptidyl arginine deiminase, type I
  • Horse(100049961) peptidyl arginine deiminase, type I
  • domestic cat(101085557) peptidyl arginine deiminase, type I
  • dog(608443) peptidyl arginine deiminase, type I

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-PADI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

Proteins

Référence du produit
Description
Espèce(s)
PADI-1 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Espèce(s)
human
PAD1, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human
PAD Cocktail, Active, recombinant,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PADI1,
Espèce(s)
human