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Merck

P2RX7

purinergic receptor P2X, ligand-gated ion channel, 7

Synonymes:
P2X7
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5027) Summary: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]
  • Mouse(18439) purinergic receptor P2X, ligand-gated ion channel, 7
  • Rat(29665) purinergic receptor P2X, ligand-gated ion channel, 7
  • Zebrafish(387298) purinergic receptor P2X, ligand-gated ion channel, 7
  • chicken(771952) purinergic receptor P2X, ligand-gated ion channel, 7
  • cow(286814) purinergic receptor P2X, ligand-gated ion channel, 7
  • domestic cat(101097922) purinergic receptor P2X, ligand-gated ion channel, 7
  • Horse(100058464) purinergic receptor P2X, ligand-gated ion channel, 7
  • dog(448778) purinergic receptor P2X, ligand-gated ion channel, 7
  • domestic guinea pig(100379234) purinergic receptor P2X, ligand-gated ion channel, 7
  • naked mole-rat(101721795) purinergic receptor P2X, ligand-gated ion channel, 7
  • Domestic Rabbit(100351535) purinergic receptor P2X, ligand-gated ion channel, 7
  • sheep(101103842) purinergic receptor P2X, ligand-gated ion channel, 7

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Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
KN-62, ≥95%, powder,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-P2RX7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-P2RX7 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
western blot
Anti-P2RX7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-P2RX7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-P2X7 Receptor Antibody, extracellular domain, Chemicon®, from rabbit,
Espèces réactives
human, rat
Application
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human P2RX7,
Espèce(s)
human