NOTCH3
notch 3
Synonymes:
CADASIL, CASIL, IMF2
Espèce(s):
Human NOTCH3 (4854), Mouse Notch3 (18131), Rat Notch3 (56761), Zebrafish notch3 (58066), dog NOTCH3 (610439), domestic cat NOTCH3 (101088469), cow NOTCH3 (789485), sheep NOTCH3 (101123554), domestic guinea pig Notch3 (100716867), naked mole-rat Notch3 (101722220)
ID UniProtKB:
ID du gène:
- Human(4854) Summary: This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008]
- Mouse(18131) notch 3
- Rat(56761) notch 3
- Zebrafish(58066) notch homolog 3
- dog(610439) notch 3
- domestic cat(101088469) notch 3
- cow(789485) notch 3
- sheep(101123554) notch 3
- domestic guinea pig(100716867) notch 3
- naked mole-rat(101722220) notch 3
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Référence du produit
Description
Espèce(s)
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anticorps anti-NOTCH 3/N3ECD, clone 1E4, clone 1E4, 1 mg/mL, from mouse,
Espèces réactives
human
Application
electron microscopy
immunocytochemistry
western blot
immunocytochemistry
western blot
Monoclonal Anti-NOTCH3 antibody produced in mouse, clone 2E2, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-NOTCH3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
Anti-Notch 3 Antibody, clone 1G17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-NOTCH3 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot