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Merck

MAP2K5

mitogen-activated protein kinase kinase 5

Synonymes:
HsT17454, MAPKK5, MEK5, PRKMK5
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5607) Summary: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011]
  • Mouse(23938) mitogen-activated protein kinase kinase 5
  • Rat(29568) mitogen activated protein kinase kinase 5
  • Zebrafish(100007679) mitogen-activated protein kinase kinase 5
  • domestic cat(101100725) mitogen-activated protein kinase kinase 5
  • cow(100295732) mitogen-activated protein kinase kinase 5
  • Horse(100052849) mitogen-activated protein kinase kinase 5
  • dog(609559) mitogen-activated protein kinase kinase 5
  • chicken(415557) mitogen-activated protein kinase kinase 5
  • sheep(101104069) mitogen-activated protein kinase kinase 5
  • Domestic Rabbit(100358715) mitogen-activated protein kinase kinase 5
  • naked mole-rat(101711080) mitogen-activated protein kinase kinase 5
  • domestic guinea pig(100732076) mitogen-activated protein kinase kinase 5

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-MAP2K5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-MAP2K5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Espèces réactives
human
Application
immunohistochemistry
western blot
ANTI-MOUSE MAP2K5 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human, mouse
Application
western blot
Anti-MEK5 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
western blot
Monoclonal Anti-MAP2K5 antibody produced in mouse, clone M1-E6, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence

western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
PD 98,059, solid,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human MAP2K5,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Map2k5,
Espèce(s)
mouse