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Merck

LRR1

leucine rich repeat protein 1

Synonymes:
4-1BBLRR, LRR-1, PPIL5
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(122769) Summary: The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
  • Mouse(69706) leucine rich repeat protein 1
  • Rat(685860) leucine rich repeat protein 1
  • Thale Cress(831521) leucine-rich repeat protein 1
  • cow(790210) leucine rich repeat protein 1
  • domestic cat(101091630) leucine rich repeat protein 1
  • dog(490676) leucine rich repeat protein 1
  • chicken(423565) leucine rich repeat protein 1
  • sheep(101119991) leucine rich repeat protein 1
  • domestic guinea pig(100719517) leucine rich repeat protein 1
  • naked mole-rat(101708337) leucine rich repeat protein 1

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-LRR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-LRR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
western blot
ANTI-PPIL5 (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human
Application
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human LRR1,
Espèce(s)
human