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Merck

GRB10

growth factor receptor-bound protein 10

Synonymes:
GRB-IR, Grb-10, IRBP, MEG1, RSS
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2887) Summary: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
  • Mouse(14783) growth factor receptor bound protein 10
  • Rat(498416) growth factor receptor bound protein 10
  • chicken(420948) growth factor receptor-bound protein 10
  • domestic cat(101083918) growth factor receptor-bound protein 10
  • cow(407210) growth factor receptor-bound protein 10
  • Horse(100052610) growth factor receptor-bound protein 10
  • dog(607755) growth factor receptor-bound protein 10
  • domestic guinea pig(100733471) growth factor receptor-bound protein 10
  • naked mole-rat(101725734) growth factor receptor-bound protein 10
  • sheep(101111275) growth factor receptor-bound protein 10

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-GRB10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-GRB10 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-Grb10 (Ser501/Ser503) Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
equine, horse, human, mouse, pig, porcine, primate, rhesus macaque
Application
western blot
Anti-GRB10 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-GRB10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Grb10,
Espèce(s)
mouse
MISSION® esiRNA, targeting human GRB10,
Espèce(s)
human