Accéder au contenu
Merck

GAD1

glutamate decarboxylase 1 (brain, 67kDa)

Synonymes:
CPSQ1, GAD, SCP
Espèce(s):
Human GAD1 (2571), Mouse Gad1 (14415), Rat Gad1 (24379), fruit fly Gad1 (38484), cow GAD1 (517552), domestic cat GAD1 (493699), dog GAD1 (478794), chicken GAD1 (395743), domestic guinea pig Gad1 (100271904), naked mole-rat Gad1 (101725846)
ID UniProtKB:
Q99259, Q53TQ7, Q9BU91, Q9UHH4
ID du gène:
  • Human(2571) Summary: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
  • Mouse(14415) glutamate decarboxylase 1
  • Rat(24379) glutamate decarboxylase 1
  • fruit fly(38484) Glutamic acid decarboxylase 1
  • cow(517552) glutamate decarboxylase 1 (brain, 67kDa)
  • domestic cat(493699) glutamate decarboxylase 1 (brain, 67kDa)
  • dog(478794) glutamate decarboxylase 1 (brain, 67kDa)
  • chicken(395743) glutamate decarboxylase 1 (brain, 67kDa)
  • domestic guinea pig(100271904) glutamate decarboxylase 1
  • naked mole-rat(101725846) glutamate decarboxylase 1 (brain, 67kDa)
  • sheep(101117393) glutamate decarboxylase 1 (brain, 67kDa)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Référence du produit
Description
Espèce(s)
RAB1472
Human GAD1 ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
MAB5406
Anticorps anti-GAD67, clone 1G10.2, clone 1G10.2, Chemicon®, from mouse,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
ZMS5406
Anti-GAD67 Antibody, clone 1G10.2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
MAB5406B
Anti-GAD67 Antibody, clone 1G10.2, Biotin Conjugate, clone 1G10.2, from mouse, biotin conjugate,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
HPA048871
Anti-GAD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
AMAB91076
Monoclonal Anti-GAD1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2911, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Référence du produit
Description
Espèce(s)
EHU085621
MISSION® esiRNA, targeting human GAD1,
Espèce(s)
human
EMU177681
MISSION® esiRNA, targeting mouse Gad1,
Espèce(s)
mouse