ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
Synonymes:
HER4, p180erbB4
Espèce(s):
Human ERBB4 (2066), Mouse Erbb4 (13869), Rat Erbb4 (59323), chicken ERBB4 (395671), dog ERBB4 (488508), Horse ERBB4 (100050182), cow ERBB4 (522419), domestic cat ERBB4 (101100073), domestic guinea pig Erbb4 (100724678), naked mole-rat Erbb4 (101725806) ...Plus
ID UniProtKB:
ID du gène:
- Human(2066) Summary: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
- Mouse(13869) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- Rat(59323) v-erb-b2 avian erythroblastic leukemia viral oncogene 4
- chicken(395671) v-erb-a erythroblastic leukemia viral oncogene homolog 4
- dog(488508) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- Horse(100050182) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- cow(522419) v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
- domestic cat(101100073) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- domestic guinea pig(100724678) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- naked mole-rat(101725806) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- sheep(101103044) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
- Domestic Rabbit(100009328) v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
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ELISA
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-erbB4/HER4 Antibody, clone 1B7 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse, rat
Application
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anti-ErbB4/HER4 Antibody, clone 8E5D0, Rabbit Monoclonal, ,
Espèces réactives
mouse, rat
Application
western blot
Anti-ERBB4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-ErbB4 Antibody, clone mAB10, clone mab10, from rabbit,
Espèces réactives
mouse
Application
ELISA
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-erbB4 Antibody, clone HFR1/2G4, clone HFR1/2G4, from mouse,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Proteins
Référence du produit
Description
Espèce(s)
ErbB4 Protein, active, 10 µg, Active, N-Terminal His6-tagged, recombinant, human ErbB4 amino acids 706-991, for use in Kinase Assays.,
Espèce(s)
human