CD46
CD46 molecule, complement regulatory protein
Synonymes:
AHUS2, MCP, MIC10, TLX, TRA2.10
Espèce(s):
Human CD46 (4179), Mouse Cd46 (17221), Rat Cd46 (29333), dog CD46 (609365), domestic cat CD46 (101094152), cow CD46 (280851), cow CD46 (616002), domestic guinea pig Cd46 (100135498), naked mole-rat Cd46 (101704640)
ID UniProtKB:
ID du gène:
- Human(4179) Summary: The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
- Mouse(17221) CD46 antigen, complement regulatory protein
- Rat(29333) CD46 molecule, complement regulatory protein
- dog(609365) CD46 molecule, complement regulatory protein
- domestic cat(101094152) CD46 molecule, complement regulatory protein
- cow(280851) CD46 molecule, complement regulatory protein
- cow(616002) CD46 molecule, complement regulatory protein
- domestic guinea pig(100135498) CD46 antigen, complement regulatory protein
- naked mole-rat(101704640) CD46 molecule, complement regulatory protein
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Référence du produit
Description
Espèce(s)
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-CD46 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Anti-CD46 Antibody, clone TRA-2-10, clone TRA-2-10, from mouse,
Espèces réactives
human
Application
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
inhibition assay
immunohistochemistry
immunoprecipitation (IP)
inhibition assay
Monoclonal Anti-CD46-FITC antibody produced in mouse, clone MEM-258, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
bovine, human
Application
flow cytometry
Monoclonal Anti-CD46-PE antibody produced in mouse, clone MEM-258, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
bovine, human
Application
flow cytometry
Monoclonal Anti-CD46-APC antibody produced in mouse, clone MEM-258, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
bovine, human
Application
flow cytometry
Proteins
Référence du produit
Description
Espèce(s)
esiRNA
Référence du produit
Description
Espèce(s)