Z226173
Nucleosil® C18 HPLC Column
5 μm particle size, L × I.D. 15 cm × 4.6 mm
Synonym(s):
Nucleosil C18
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About This Item
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
Agency
suitable for USP L1
product line
Nucleosil®
feature
endcapped
manufacturer/tradename
Nucleosil®
extent of labeling
15% Carbon loading
parameter
≤70 °C temp. range
400 bar pressure (5801 psi)
technique(s)
HPLC: suitable
L × I.D.
15 cm × 4.6 mm
surface area
350 m2/g
matrix
octadecyl
matrix active group
C18 (octadecyl) phase
particle size
5 μm
pore size
100 Å
separation technique
reversed phase
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Application
- Quantification and Validation of Stability-Indicating RP-HPLC Method for Efavirenz: Demonstrates the utility of Nucleosil® C18 HPLC Column in pharmaceutical analysis, particularly in quality control and stability testing of Efavirenz, ensuring compliance with regulatory standards (Gurumukhi VC, Bari SB, 2022).
- Development of new method for simultaneous analysis of piracetam and levetiracetam: This study uses the Nucleosil® C18 column to develop robust methods for analyzing neurological medications in pharmaceuticals and biological fluids, contributing to drug stability studies (Siddiqui FA et al., 2014).
- HPLC method for determination of biologically active epoxy-transformers of treosulfan: The column′s application in plasma analysis highlights its role in pharmacokinetic studies, offering precise measurements critical for dosing and therapeutic monitoring (Główka FK et al., 2012).
- HPLC analysis of mitoxantrone in mouse plasma and tissues: Illustrates the column′s effectiveness in a pharmacokinetic study, underscoring its importance in the preclinical evaluation of cancer therapies (An G, Morris ME, 2010).
- Development and validation of an HPLC method for vancomycin: This application in a pharmacokinetic study highlights the column′s critical role in the development and validation of methods for antibiotic analysis, ensuring therapeutic efficacy and safety (Jesús Valle MJ et al., 2008).
Legal Information
Nucleosil is a registered trademark of Macherey-Nagel GmbH & Co. KG
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