SAB2501668

Anti-UCHL1 (C-terminal) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Synonym(s): PARK5, PGP9.5, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: goat
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: canine, bovine, rat, rabbit, pig, human
• technique(s): immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProt accession no.: P09936
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... UCHL1(7345)

Description

General description

Ubiquitin C-terminal hydrolase L1 (UCHL1) is a deubiquitinase which is part of the ubiquitin proteasome system (UPS). The protein is expressed in the nervous system and gonads. The gene encoding UCHL1 is localized on human chromosome 4p13.

Immunogen

Peptide with sequence EVRFSAVALCK, from the C-terminal region of the protein sequence according toNP_004172.2

Biochem/physiol Actions

Ubiquitin C-terminal hydrolase L1 (UCHL1) has a role in epithelial-mesenchymal transition. It also has roles in invasion and in the cell cycle. UCHL1 catalyzes the hydrolysis of carboxy-terminal ubiquitin esters and amides. The protein has been associated with various cancers.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable